Biomarkers could lead to better treatments for CF patients
Recently two new
biological markers are identified for cystic fibrosis (CF), a inherited disease
which affects children and young adults, leaving them with lifelong health
complications including gastrointestinal problems and persistent lung
infections. The recent research
shed new light on the underlying mechanisms of Cystic Fibrosis which could lead
to improved prognosis and exceptional therapies for a disease which is quite
variable, affecting different children in different ways.
There are chemical
signatures in sweat that tell us an infant has CF or not. The chemical
indicators detected in sweat that could complement the gold standard for CF
diagnosis is with the help of sweat chloride test. The test is commonly used in
universal neonatal screening programs and measures the concentrations of salt.
Increased sweat chloride confirms that an infant actually has CF.
"Sweat contains
lots of information related to human health and there are also some unexpected
chemicals associated with CF that can be used for the diagnosis of this genetic
disease. Using a specialized technique, several unknown chemicals beyond
chloride that were consistently associated with babies who had CF, including
two different drug and environmental compounds the infants secreted in sweat at
much reduced concentration levels were identified.
These biomarkers also point
to other intrinsic mechanisms that contribute to the advancement in Cystic
Fibrosis and could lead to better therapeutic interventions earlier in life.
To know more about this
evolving topic let us join the upcoming huge conference i.e International conference
on Cystic Fibrosis which is going to be held during September 20-21, 2018 at
Dubai, UAE which will be a definitively informative platform for all, who are
going to attend the conference.
For further information, kindly visit:
Edward William
Program Manager
Cystic fibrosis 2018
Kemp House152 City Road, London, UK
Tel: +1 702-508-5200 Ext: 8122
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