Biomarkers could lead to better treatments for CF patients


Recently two new biological markers are identified for cystic fibrosis (CF), a inherited disease which affects children and young adults, leaving them with lifelong health complications including gastrointestinal problems and persistent lung infections. The recent research shed new light on the underlying mechanisms of Cystic Fibrosis which could lead to improved prognosis and exceptional therapies for a disease which is quite variable, affecting different children in different ways.

There are chemical signatures in sweat that tell us an infant has CF or not. The chemical indicators detected in sweat that could complement the gold standard for CF diagnosis is with the help of sweat chloride test. The test is commonly used in universal neonatal screening programs and measures the concentrations of salt. Increased sweat chloride confirms that an infant actually has CF.

"Sweat contains lots of information related to human health and there are also some unexpected chemicals associated with CF that can be used for the diagnosis of this genetic disease. Using a specialized technique, several unknown chemicals beyond chloride that were consistently associated with babies who had CF, including two different drug and environmental compounds the infants secreted in sweat at much reduced concentration levels were identified.

These biomarkers also point to other intrinsic mechanisms that contribute to the advancement in Cystic Fibrosis and could lead to better therapeutic interventions earlier in life.

To know more about this evolving topic let us join the upcoming huge conference i.e International conference on Cystic Fibrosis which is going to be held during September 20-21, 2018 at Dubai, UAE which will be a definitively informative platform for all, who are going to attend the conference.

For further information, kindly visit:
Edward William
Program Manager
Cystic fibrosis 2018
Kemp House152 City Road, London, UK
Tel: +1 702-508-5200 Ext: 8122



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